A 65-year-old man, a smoker with obstructive pulmonary disease, developed an erythematous infiltrating skin lesion with a scarring, hyperkeratotic crust that had been evolving for 5 months. A skin biopsy with histopathology indicated large numbers of yeast-like organisms surrounded by mucinous capsular material forming mucoid masses in the dermis. The mucinous capsular materials were stained red and black with mucicarmine and Grocot–Gomori silver stain, respectively.
Microsporum audouinii is an anthropophilic dermatophyte fungus associated with skin and scalp mycosis and has reemerged recently. It is one of the most common causative agents of tinea capitis in Central African countries and its prevalence has increased in other countries, especially in Europe.1,2 Between 2005 and 2021, 6 microsporum audouinii outbreaks were reported: two from Denmark and the remaining from Germany, Sweden, Switzerland, and Australia.
We report the case of a 6-year-old girl with allergic contact dermatitis and polysensitization. Patch testing performed with the baseline series, cosmetic series, and nail products showed positive results for balsam of Peru, propylene glycol, cobalt chloride, Amerchol L-101, ethylene glycol dimethacrylate, and triethylene glycol dimethacrylate. She had a history of using her mother’s perfumes, jewelry, and skincare products, having colored hair highlights, and using nail polish. The incorporation of adult typologies into the child’s world and the aesthetic pressure on pediatric patients to consume products such as hair dyes, accessories, perfumes, creams, moisturizers, and nail polish contribute to the increased prevalence of contact dermatitis in this age group.
Urticaria is a condition characterized by the presence of hives, angioedema, or both. It can be classified according to its duration as acute, when it persists for less than 6 weeks, or chronic, when it persists for more than 6 weeks and greatly affects quality of life. Updated recommendations on diagnosis and management are developed by experts from all over the world who meet every 4 years in Berlin and review all new evidence that supports changes to the international guideline. This paper discusses the main recommendations proposed in the current version of the international guideline.
A 32-year-old man with a history of human immunodeficiency virus (HIV) infection, CD4 cell count of >400/μL, and an undetectable viral load copies/mL, presented with verrucous mild itchy lesions on the right lower limb that had appeared 3 years prior. A skin biopsy revealed areas of verruca vulgaris with smaller areas of melanoacanthoma.
We describe two cases of cutaneous protothecosis that occurred in our dermatology department last year. Since 1983, only twelve cases have been described in the country.1,2 There are about two hundred cases reported worldwide on all continents, but with a slightly higher number of cases concentrated in Asia. There is no climatic predilection in the incidence of cases, which is increasing and has been estimated at an annual average of 6– 7 cases.
Chronic granulomatous disease (CGD) is an inborn error of phagocyte immunity and occurs as a resulto f mutations that affect components of the NADPH oxidase enzyme. Patients are susceptible to serious and lethal fungal and bacterial infections. The aim of this paper is to report a case an infant with CGD who presented clinical manifestations of intrathoracic tuberculosis (TB) in the pseudotumoral and bone form, which started in the neonatal period. The diagnosis of CGD was performed using the DHR test and, after starting prophylaxis with sulfamethoxazole-trimethoprim and itraconazole, the patient remained clinically stable. The mother and sister also had altered DHR, genetic analysis revealed an X-linked mutation in exon 2 of the CYBB gene c.58G>A, leading to an alteration in G20R. It is essential that the diagnosis is made as early as possible, in order to establish guidelines for Family members and adequate treatment, thus reducing infectious complications and improving prognosis.
Atopic dermatitis (AD) is a chronic inflammatory disease and the assessment of the quality of life
and the severity of the disease is important to help the clinical and therapeutic approach.
Acute urticaria is a commom childhood disease with detailed clinical history and physical examination essential for the etiological diagnosis. The pediatrician should be aware of the main triggering factors, including viral infections.
Esofagitis eosinófila es una enfermedad inflamatoria crónica caracterizada por un infiltrado de eosinófilos en el esófago, siendo estimada en 1:10.000. Es distinta de la enfermedad del reflujo gastroesofágico (DRGE), a pesar de que los pacientes comparten síntomas semejantes. No está bien establecido el papel de la alergia en el proceso, sin embargo la mejora o resolución del proceso con la dieta de exclusión alimentaria indica un papel de la alergia alimentaria en algunos pacientes.
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