Perioral dermatitis is characterized by “red bumps around the mouth” (small inflammatory papules and pustules). It can affect the mouth and, in some cases, the nose and eyes, so-called periorificial dermatitis. It can affect children, but it is more common in women between 20 and 45 years old. The etiology is unknown. In some patients, it is caused by the chronic use of topical corticosteroids. Other related factors are infection by Candida albicans or by bacteria, use of fluoride toothpaste and some cosmetics. At the site of the lesions, the patients have sensitivity or burning and itching. When in contact with various products, the skin – being sensitive – becomes redder and worsens the dermatitis. Perioral dermatitis can often be confused with rosacea, acne vulgaris and even contact dermatitis. Blepharitis (inflammation of the eyelids) and conjunctivitis may be associated with the rare cases of granulomatous periorificial dermatitis. The diagnosis is clinical. In cases with atypical presentation or non-response to treatment, skin biopsy may be considered. Treatment should be guided by the attending physician, usually with topical antibiotics and calcineurin inhibitors. In the most extensive cases or with little response clinically, oral antibiotic therapy may be indicated. Avoid self-medication! If in doubt, seek medical attention.
Reference:
Tolaymat L, Hall MR. Perioral Dermatitis. 2022 Sep 5. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2022 Jan–. PMID: 30247843.